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4.83 out of 5 based on 12 customer ratings
12 reviews

Our proprietary, patented Neo40 formula out of the University of Texas Health Science Center’s N-O Discovery Program, is a convenient daily supplement that helps to quickly increase your body’s Nitric Oxide. In fact, our formula represents a breakthrough in N-O delivery compared to standard L-Arginine supplements or traditional diets aimed at supporting heart health. Neo40 may help promote:

  • Healthy blood pressure levels
  • Cardiovascular and heart health
  • Increased circulation throughout the body
  • Healthy arterial function
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Customer Reviews

Read what our customers have to say about Neo40®. Leave a review to share your own feedback.

12 reviews for Neo40®

  1. 5 out of 5

    I started using Neo40 over a year ago in hopes that it would help me re-establish a healthy lifestyle. After turning 50, I tried to reverse my weight gain, reduce my blood pressure and control my blood sugar levels by walking daily, but I found myself exhausted shortly into each jaunt around the block, resulting in me needing a nap. Two years later, my weight, blood pressure and sugars were worse than ever.

    After reading about nitric oxide and its role in the body, it made sense that Neo40 could help my exercise fatigue. I started using it, and almost immediately I felt I had more endurance. My walks seemed less strenuous even though I was increasing my pace. I was very satisfied with the results I initially experienced, so I continued to use it.

    Fast forward – I am once again a productive person. I don’t spend my days napping and watching TV. I have reduced my weight from 200 lbs to 160 lbs (and still losing -slowly). My A1c and daily glucose levels are normal (without insulin). I’m not claiming that Neo40 is a magic pill, but I am convinced it was part of my success. It made it possible for me to tolerate exercise, and my daily walks have enabled me to reach my health goals after years of trying. Today Neo40 is part of my daily routine, and my husband (the skeptical physician) is using it as well.

  2. 5 out of 5

    Ordering was easy. Shipping was timely. I was able to track my package. The product is as advertised. I wish it was less expensive, but as I said, it does deliver on it’s promises.

  3. 5 out of 5

    This is just incredible stuff. Felt a difference in my stamina and well being in just a few days. I’m 63 and feel so much better. I think it has also checked my metabolism and helped me lose 20# in 2 months. Fast shipping. Several Discounts available!!

  4. 5 out of 5

    This product has done more to help my BP readings than anything I have taken, eaten or been prescribed by a Doctor. From the first week I started the replenishment program I had instant and lasting benefits. I am now moving into the maintenance mode and will see if my BP stays good.

  5. 4 out of 5

    at time of next routine bloodwork my doctor said "you are amazingly healthy",something not said previously following bloodwork results

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Neo40 Product Details

Eating right and exercising regularly may not be enough.

Nitric Oxide has been dubbed “the miracle molecule” and the discovery of its effects on the cardiovascular system earned a Nobel Prize. Our scientists have built on that discovery, developing Neo40, which helps to promote healthy circulation and support healthy blood pressure levels in the body through artery dilation and oxygenation of the blood. Eating right and exercising regularly may not be enough to help maintain your Nitric Oxide at optimal levels. That’s why Neo40 should be a part of your daily regimen.

N-O is the foundation of our health, essential and tied to most of the body’s major physiological systems. Without it, we can’t live.

That’s why we’ve spent years scientifically researching and studying N-O. And why we created Neo40, a concentrated, clinical grade, cardiovascular solution. Proprietary, one-of-a-kind and patented, Neo40 is a daily supplement that helps to rapidly produce Nitric Oxide in your body, as well as supports the body’s ability to produce its own N-O over time. In fact, it is the only technology in the world, out of the University of Texas Health Science N-O Discovery Program, that generates authentic Nitric Oxide gas and supports the enzyme that makes Nitric Oxide in the body.

Great tasting and convenient, Neo40 works with your body to produce N-O, which has a naturally short life span in the linings of our blood vessels. That short life span means it’s important to keep N-O at optimal levels in the body, especially over the age of 40 when supporting optimal levels of N-O becomes vitally important to our overall cardiovascular health.  

Optimum at over 40.

For those over the age of 40, it’s important to help keep Nitric Oxide at optimum levels in the body. Neo40 was created to help combat this and support N-O levels so your body may help promote:

  • Healthy blood pressure levels
  • Cardiovascular and heart health
  • Increased circulation throughout the body
  • Healthy arterial function

Formulated from years of research.

Neo40 is based on the work of renowned Nitric Oxide researcher and HumanN’s Chief Science Officer, Dr. Nathan Bryan and the University of Texas Health Science Center. His ongoing research on the effects of Nitric Oxide on circulation and health inspired the formulation of Neo40, created to activate and restore N-O. Backed by 15 years of continuous research, Dr. Bryan has lead the field of N-O application and conducted seven successful clinical trials on HumanN N-O products to ensure that they are safe and efficacious, with another five clinical trials underway presently.

What makes Neo40 different than other products on the market, including L-Arginine supplements, is that our patented formula represents a breakthrough in N-O delivery. In fact, studies suggest that if you’re over 40 or have compromised endothelial function, L-Arginine is unlikely to work for you.

Neo40 is formulated to boost the efficiency of the body’s nitrate pathway so that more Nitric Oxide is available when and where it’s needed. Each tab contains 420mg of our patented Nitric Oxide blend, with added vitamin C and B12.

Taste Profile
One tab with one very pleasant taste.

Getting your Nitric Oxide is easier and tastier than you may have thought. Neo40 has a great fruity taste and dissolves in your mouth quickly.

Replenishment Program
Make Neo40 part of your routine.

Neo40 should be a part of your daily routine for healthy Nitric Oxide levels. After all, Nitric Oxide levels and our ability to maintain optimal levels of N-O diminishes with each passing decade, starting in our 20s. Enroll in our replenishment program and automatically receive Neo40 each month with free shipping. Or choose to receive a three-month supply, our best value. It’s free to join and you can cancel at any time by contacting us at 1.855.636.4040.

We stand behind our products.

We want to bring the best functional foods and supplements to humans everywhere. So if you’re not completely satisfied with any of our products, you can return them to us within 90 days of your order date, no questions asked.


One tab, once a day.

Take one tab daily and allow it to dissolve on your tongue. Do not swallow the tab whole or place under your tongue. You can take two tabs daily during the 30-45 day restoration loading phase. After 30-45 days, take only one tab daily. Never take more than two tabs in a 24-hour period. Each Neo40 box contains a one-month supply, or thirty tabs.

Consult your physician prior to taking Neo40 if you’re taking 1) organic nitrate medications such as nitroglycerin or isosorbide, 2) erectile dysfunction drugs, since the combination of the two may cause an unsafe drop in blood pressure, 3) blood thinner medications, or 4) medications related to lowering blood pressure. Discontinue use and contact your physician if you experience dizziness or fainting.

Nutritional Information

Neo40 Ingredients: Vitamin C, Vitamin B12, Proprietary Nitric Oxide Blend (Beet Root Powder (root), Hawthorn Berry Extract (berry), L-citruline, Sodium Nitrite.

Other Ingredients: mannitol, modified cellulose, xylitol, natural flavors, magnesium vegetable stearate, stevia, silica.


Customer Testimonials

I went in for a physical and my blood pressure was great.

Annette G. from  Ohio

The result is super powerful, positive from day one. The product is commendable. PERIOD!!

E. Nangle from Canada

I started using Neo40 over a year ago. I needed a good heart product and we needed to know if it would work for our clients.  I feel so much better and my heart is testing to be better, when I take the neo40.  Our clients love the Neo40 and love the way they feel on it.*

Dr. Jan Van Meter from Texas

*This information is based on these healthcare practitioners use of Neo40 in their practices. Clinical studies on Neo40 suggest it may help support health NO, blood pressure, and exercise endurance.

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We stand behind our products.

We want to bring the best functional foods and supplements to humans everywhere.

So if you’re not completely satisfied with any of our products, simply return them to us within 90 days of your order date, no questions asked.

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